Organised by Health&Infirmity Medical LTD

Programme

Conference schedule for ITTMEE 2026

08:10 08:50
Registration

Registration

Attendees, who have opted for on-site registration, are kindly requested to report not later than 08:50am to the registration desk to secure a timely start of the program.
Foyer of "Triaditza" meeting room 40 min
09:00 09:15
Networking

Welcome and Introduction

Welcome address of local organising committee and ISHLT leadership, short introduction and housekeeping rules.
Dr Katharina Wassilew Meeting room "Triaditza" 15 min
09:15 09:45
Keynote Lung

Surgical aspects of lung transplantation

The presentation highlights shortly the patient selection criteria and demonstrates how a lung transplant surgery is performed. Anatomic landmarks of the explanted lung and anastomoses sites are being explained and the expectation of the information of the content of a histopathology report and the importance for patient management are outlined. 10 minutes of the slot is reserved for Q&A. 
Prof John Dunning Meeting room "Triaditza" 30 min
09:45 12:00
Workshop Lung

Lung pathology of native lungs

This track aims to provide the opportunity to engage with internationally leading experts, foster new connections and learn about the latest advancements and cutting-edge developments in lung transplantation.
Further, it  aims to provide the platform to foster inter- and cross-disciplinary dialogue, encourage presentation of fresh perspectives and develop future projects for researchers, educators, physicians and allied health professionals working in this field, inviting interested public to share their prospective.
This block aims to provide an inside on the pre-transplant diagnostic cycle and on the lung transplant process itself, providing the perspective of different specialties.
Dr Izidor Kern, Prof Anja Roden, Prof John Dunning Meeting room "Triaditza" 135 min
09:45 10:15
Lecture Lung

Pre-transplant evaluation of native lungs

This session aims to discuss with the audience the spectrum of donor lung lesions and to provide guidance on the wording of the preliminary diagnosis, whilst focussing on the implication of the wording on transplantability of the donor organ.  The slot includes 10 min Q&A session.
Prof Anja Roden Meeting room "Triaditza" 30 min
10:10 10:30
Lecture Lung

Guidance on minimum sampling of expected findings with clinicopathological correlation

This is a hands on session, which aims to provide guidance on standard operating procedures regarding examination and minimum sampling of explanted lungs, demonstrating an expert's approach to handling previously histologically diagnosed concordant, as well as histologically discordant cases, addressing clinico-pathological inconsistencies. This session includes case demonstrations.
Dr Izidor Kern Meeting room "Triaditza" 20 min
10:30 11:00
Break Lung

Coffee break and e-poster presentation (surgical lung pathology)

Grab a snack and a coffee, use the time to network, exchange ideas or just relax in front of the fountains in the beautiful park bordering with the venue, although the audience is invited to join the e-poster session.

Please consider joining us at the e-poster session on "surgical lung pathology"! 
Poster presenters are encouraged to prepare a short 5 minute presentation. 
Online participants are also encouraged to submit abstracts.
Showcase your knowledge, take the chance to win the best poster award and the eligibility to publish your research on discounted rates!
Foyer Meeting room " Triaditza" 30 min
11:25 12:00
Workshop Lung

Incidental findings with clinicopathological correlation

This is a hands on session, demonstrating an expert's approach to handling histologically discordant cases between frozen section diagnosis and final histological diagnosis, in addition addressing the approach to inconsistencies between clinico-pathological or pathologo-radiological findings. 
The diagnostic approach will be demonstrated using live video microscopy for cases from the clinical practice. During demonstrations, the input from the audience will be requested and the clinicopathological discussion will be simulated by the presenters.

This session includes a Q&A and bring your own case session (11:45 am-12:00pm).
The technical presentation will be supported by Corina Turner.


Dr Izidor Kern, Prof Anja Roden, Prof John Dunning Meeting room "Triaditza" 35 min
12:00 12:30
Lecture Lung

Clinical management of lung transplant patients

Dr Gerovasili will outline the postoperative clinical management and immediate clinical complications of lung transplant patients, as well as the most commonly encountered pathologies responsible for decline of pulmonary allograft function in the late post transplant course. She will also provide her perspective on controversies and emerging topics in lung transplantation, including relevance and treatment of newly formed DSA to improve the outcome of the lung transplant.
Dr Gerovasili will deliver her presentation online, but will remain available to answer your questions. The slot includes 10 min Q&A. 
Dr Vasiliki Gerovasili Meeting room "Triaditza" 30 min
12:30 16:30
Workshop Lung

Factors influencing the outcome of the pulmonary allograft

This interactive session will provide an overview of factors influencing the outcome of the pulmonary allograft from the perspective of different specialties.
Different presentation modes will be used and the audience is encouraged to engage actively in discussion on diagnostic approach and differential diagnoses, as well as to share their experience.
12:30 13:00
Lecture Lung

My approach to histological assessment of the pulmonary allograft

This session aims to provide an approach to assess the provided biopsy material for adequacy for diagnostic assessment,  and an overview of the current guidelines with regard to grading criteria for acute cellular rejection and bronchiolitis obliterans, whilst addressing the gaps in the current classification and highlighting the approach to exclude differential diagnoses mimicking acute cellular rejection, as infection, aspiration and drug reaction.
Histological sections will be projected and assessed on-site. The audience will engage actively in the assessment of the histological material and the relevance of the histological diagnosis on the clinical management will be discussed.
13:00 14:00
Break Lung

Lunch break

Grab your lunch and some water, use the time to network, exchange ideas or just relax in front of the fountains in the beautiful park bordering with the venue.

Foyer of Meeting room "Triaditza" 60 min
14:00 14:45
Workshop Lung

Oh dear- what else? Histological assessment of other forms of rejection and unexpected findings.

This interactive workshop highlights the necessity to evaluate the provided lung allograft tissue for other forms of rejection, including chronic airways rejection, vasculopathy and antibody mediated rejection. The question- where are we and where do we need to go?- will be elaborated on.
In addition, other post-transplant findings (as PTLD, other neoplasms, ....) are being discussed.
Live microscopy using a digital platform will be used to discuss selected cases. The audience is being encouraged to engage actively in the discussion and to share their experience.
Dr Izidor Kern, Prof Anja Roden Meeting room "Triaditza" 45 min
14:30 14:45
Lecture Lung

Lung infections in immunocompromised patients

Prof Zinserling is presenting his experience with working with pulmonary infections and is also going to elaborate on uncommonly diagnosed viral lung infections, which are likely under diagnosed in this patient population.
Prof Vsevolod Zinserling Meeting room "Triaditza" 15 min
15:00 15:30
Lecture Heart and Lung

Do not forget about endocrine sequelae!

Although endocrine pathology is commonly encountered after transplantation and requires lifelong monitoring and management, symptoms are often mistaken for other diagnoses and patient referral is often delayed. Associate Totomirova is going to focus on the most common endocrine complications, such as diabetes and osteoporosis, which are common after solid organ transplantation and will provide an overview of diseases which may be encountered after transplantation. 
The session includes 10 min Q&A. The audience is encouraged to share their experience and to engage in the discussion.
Lt col, Assoc Prof Tzvetelina Totomirova Meeting room "Triaditza" 30 min
15:30 16:00
Break Lung

Coffee break and e-poster presentation (pulmonology and lung pathology)

Grab a snack and a coffee, use the time to between the sessions to network, to exchange ideas or just enjoy the view of the fountains in the beautiful park bordering with the hotel venue.

Please consider joining us at the e-poster session on "pulmonology and lung pathology"! 
Poster presenters are encouraged to prepare a short 5 minute presentation. 
Online participants are also encouraged to submit abstracts.
Showcase your knowledge, take the chance to win the best poster award and the eligibility to publish your research on discounted rates!


16:00 16:30
Panel Discussion

Brainstorming and bring your own case

This session aims to provide expert opinion on real life cases, representing a diagnostic challenge to the audience. Participants are encouraged to upload case information and histological slides upfront, but video microscopy would be available on-site.
In order to advance science, an if the time allows, the audience is further encouraged to engage in the discussion of to-date not well-studied aspects/diseases in form of a brainstorming session and to signal availability to  contribute to research. 
16:30 17:00
Lecture Lung

Challenges related to surgical training and set up of a lung transplant program in Eastern Europe- my personal perspective.

Associate Prof Minchev is sharing his personal perspective on establishing a lung transplant program and is going to discuss the obstacles which have prevented a successful launch during the past two decades.
The session includes 10 min Q&A.
Associate Prof Tzvetan Minchev Meeting room "Triaditza" 30 min
17:00 17:30
Lecture Heart and Lung

Civil and criminal proceedings in cases of violation of the transplantation and blood transfusion directive.

Associate Prof Maria Grozeva is giving an overview and sharing her expertise concerning violations of the transplantation and blood transfusion directives based on real cases and will highlight the consequences for both patients and medical staff involved. 

Associate Prof Maria Grozeva Meeting room "Triaditza" 30 min
17:30 18:00
Lecture Emerging technologies

The power of emerging technologies- walking the line.

The presentation highlights the importance of an international tracing system of organs, (in addition to the established ones, like the European Eurotransplant and Scanditransplant) in the era of organ shortage, human and organ trafficking and migration on the background of often unidentified infectious and malignant diseases of the donor at time of transplant. Prof Radeva will explain and elaborate on the limitations of emerging technologies, as blockchain.

We conclude the day with this presentation. We hope you enjoyed the sessions, engaged in the discussions, felt comfortable and at ease communicating your point of view and are now going to join us at the Welcome Networking Reception. 
Prof Irina Radeva Meeting room "Triaditza" 30 min
18:15 20:00
Networking

Welcome Networking Reception

Dear colleagues,
Congratulations! You've braved the day! Let's meet outside the meeting room, where a variety of alcoholic and non-alcoholic complementary beverages awaits. 
Please do not leave before the group Photo has been taken! 
Grab a glass, enjoy the food and take the opportunity to connect and exchange your views and ideas with your peers in an informal atmosphere. 
 
We are looking forward to reconnect tomorrow with all of you!
Foyer of meeting room "Triaditza" 105 min
09:00 09:05
Registration Heart

Welcome back!

Good to have you back! 
We kickstart the day with a short welcome address and a reminder of the housekeeping rules.
Dr Katharina Wassilew Meeting room "Triaditza" 5 min
09:00 11:30
Lecture Heart

Pre- heart transplant pathology

This track aims to provide the opportunity to engage with internationally leading experts, foster new connections and learn about the latest advancements and cutting-edge developments in heart transplantation.
Further, it  aims to provide the platform to foster inter- and cross-disciplinary dialogue, encourage presentation of fresh perspectives and develop future projects for researchers, educators, physicians and allied health professionals working in this field, inviting interested public to share their prospective.
This block aims to provide an inside on the pre-transplant diagnostic cycle and on the heart transplant process itself, providing the perspective of different specialties.
09:05 09:30
Keynote Heart

Clinical aspects to consider in heart transplantation

This talk will review peri-transplant management, who, when and how to treat sensitized heart transplant candidates, strategies for desensitization, and factors of longevity , as criteria to guide listing for heart transplant. 
Prof Howard Eisen Meeting room "Triaditza" 25 min
09:30 10:00
Keynote Heart

How to perform a heart transplant

Prof Dunning will outline the process of heart transplantation, highlighting anatomic landmarks, and their importance for the proper, clinically relevant histologic assessment of the explanted native heart.  
This session includes 10 min Q&A.
Prof John Dunning Meeting room "Triaditza" 30 min
10:00 10:30
Workshop Heart

Expected and Puzzling findings in explanted native hearts

Dr Lianou's presentation is focussed on clinico-pathological correlation when examining the native explanted heart macroscopically and histologically. She is going to elaborate on in view of the clinical history expected, as well as on puzzling histopathological findings under the motto: What the heck is this? Little too late- the most common but also clinically totally unexpected findings in explanted cardiac specimens. 
This session is a designed as a Workshop with case demonstration. Active participation from the participants is particularly welcome.
Dr Maria Lianou Meeting room "Triaditza" 30 min
10:30 11:00
Break Heart

Coffee break

Grab a coffee, get to know and exchange your views with colleagues, relax and recharge or join us at the e-poster session.
Foyer of "Triaditza" meeting room 30 min
10:40 11:00
Panel Discussion Heart

E-Poster session on native heart pathology

Grab a snack and a coffee, use the time to network, exchange ideas or just relax in front of the fountains in the beautiful park bordering with the venue, although the audience is invited to join the e-poster session.

Please consider joining us at the e-poster session on "native heart pathology"! 
Poster presenters are encouraged to prepare a short 5 minute presentation. 
Online participants are also encouraged to submit abstracts.
Showcase your knowledge, take the chance to win the best poster award and the eligibility to publish your research on discounted rates!

Dr Katharina Wassilew, Prof Howard Eisen, Prof John Dunning Meeting room "Triaditza" 20 min
11:00 11:30
Lecture Heart

Don't forget the bugs! Which cardiac infections should not be missed!

The presentation aims to provide an overview of most commonly encountered histologically detectable infections, which may have an impact on the native heart or cardiac allograft and stresses on the importance of differential diagnosis of in recent years less diagnosed diseases, as tuberculosis and HIV.
This session included 10 min Q&A.

Prof Vsevolod Zinserling Meeting room "Triaditza" 30 min
11:30 12:00
Lecture Heart

The value of the endomyocardial biopsy in monitoring the cardiac allograft.

This session focusses on pathological classification and diagnosis of ACR and AMR, pitfalls in differentiating rejection from infection, morphological correlates of HLA, non-HLA positive results to tissue findings, comments on the timeframe when cfDNA results reflect histopathological findings and highlights advantages and disadvantages of pathological examination, considering essential contribution of pathology to development of understanding of etiology of rejection as for instance in classification of biopsy negative AMR. Furthermore, the importance of tissue investigation to exclude other pathologies, as TVP, neoplasia, recurrence of autoimmune disorders in form of granulomatous inflammation is being highlighted. 
The audience is encouraged to share their experience and perspective, if desired anonymously, yet in an interactive way. 
Clinical input will be provided by Prof John Dunning, as required.
Dr Katharina Wassilew, Prof John Dunning Meeting room "Triaditza" 30 min
11:30 15:00
Lecture Heart

Post-heart transplant pathology

This block aims to provide an inside on the heart transplant process itself and on the post-heart transplant diagnostic cycle, providing the perspective of different specialties.
12:00 12:30
Lecture Heart

A deep dive into immunology- Antibodies, antibody-mediated rejection and..... how to deal with them?

Donor-specific HLA antibodies (DSAs) contribute to antibody-mediated rejection (AMR), acute cell-mediated rejection (ACR) and cardiac allograft vasculopathy (CAV) after heart transplant. However, a number of heart transplant patients present with AMR in the absence of DSAs, suggesting antibodies against non-HLA antigens may be associated with an increased risk of AMR and poor outcomes during follow-up. The role of biomarkers in immunology in differentiating infection from rejection and emerging technologies for differentiation between the different pathologies is being discussed.
This session includes 10 min Q&A.
Assistant Prof Andriana Nikolova Meeting room "Triaditza" 30 min
12:40 13:00
Keynote Heart

The impact of hematologic disorders on the outcome of Heart transplantation

The objective of this session is to provide an overview and to raise awareness of the most common hematologic pathologies impacting the outcome of heart transplantation, which may be caused by a plethora of factors, including, but not restricted to medication, immune status, infection, and immune mediated depletion of a coagulation factor.
The audience is encouraged to share their experience. The session includes a short Q&A.
Associate Prof Martin Weihrauch Meeting room "Triaditza" 20 min
13:00 13:40
Break Heart

Refreshment break

Grab a snack and a coffee, use the time to network, exchange ideas or just relax in front of the fountains in the beautiful park bordering with the venue, although the audience is invited to join the e-poster session.

Foyer of Meeting room "Triaditza" 40 min
13:10 13:40
Panel Discussion Heart and Emerging technologies

E-Poster session on "Post-transplant heart pathology" and "Emerging pathologies"

Grab a snack and a coffee, use the time to network, exchange ideas or just relax in front of the fountains in the beautiful park bordering with the venue, although the audience is invited to join the e-poster session.

Please consider joining us at the e-poster session on "post-transplant heart pathology" and "emerging technologies"! 
Poster presenters are encouraged to prepare a short 5 minute presentation. 
Online participants are also encouraged to submit abstracts.
Showcase your knowledge, take the chance to win the best poster award and the eligibility to publish your research on discounted rates!
Dr Maria Lianou, Prof Irina Radeva, Prof John Dunning Meeting room "Triaditza" 30 min
13:40 14:00
Workshop Heart

Bringing it all together- my approach to solving difficult cases

Dr Maria Lianou is sharing her experience with the audience on how to approach "difficult" cases.
Dr Lianou's aim is to highlight the importance of correlation of clinico-pathological information, the consideration of all relevant differential diagnosis and to outline an easy to follow step-by-step approach to reaching the diagnosis. This is an interactive session, mimicking a clinical setting, in which the clinical information will be provided by Assistant Prof Andriana Nikolova. 
After this session, the audience should have gained awareness of the importance of acquiring complete clinical information before assessing cardiac allograft cases and to be have gained knowledge about the main differential diagnoses of the presented cases.
This session aims to encourage as much interaction as possible between presenter and audience.   
The technical part of the presentation is kindly supported by Corina Turner.
Dr Maria Lianou, Assistant Prof Andriana Nikolova Meeting room "Triaditza" 20 min
14:00 14:20
Lecture Heart

Chasing after the events- why haven’t we considered establishing multidisciplinary team meetings to achieve reproducible results before - from a adult cardiologist's perspective

In this talk, the presenter is going to stress on the necessity to apply a wide range of established and newly developed tests in the diagnostic setting as diagnostic standard in order to reach reproducible results, to advance the understanding of the disease and to improve the patient outcome. But mainly, the importance of interdisciplinary communication and contribution of each and every specialty involved in the diagnostic process and for clinical decision taking is being highlighted and the concept of an obligatory MDT meeting and the use of an interdisciplinary unified language is being proposed.

Prof Howard Eisen Meeting room "Triaditza" 20 min
14:40 15:00
Lecture Heart

The future of heart transplantation

Prof Potapov's presentation aims to present his perspective on current developments and trends in heart transplantation, including mechanical circulatory support systems, total artificial heart and xenotransplantation.
The presenter will be delivering his presentation remotely but will be available to taking questions from the audience.
Prof Evgenij Potapov Meeting room "Triaditza" 20 min
15:00 15:05
Panel Discussion Heart

Farewell

Congratulations! You have expanded your network whilst exchanging your experience and gaining knowledge on the professional perspective of the Faculty on the presented topics. 
All Faculty members were impressed by your input and are now announcing the winner of the "best poster award". 
Don't disconnect now- we are about to take a group photo of all zoom participants. 
After taking the screenshots, we round the day and therewith the meeting off and would love to hear from you about your experience. You are kindly requested to share your impressions and suggestions how to improve this event format, to send us your best pictures for publication on the websites and to keep in touch with the Faculty.
We are looking forward to welcome many, if not all of you next year. In the meantime, keep in touch and stay tuned!
If you haven't already done so, we hope you take the chance to join Corina Turner for her demonstration of the "Smart in Media" platform.
Thank you!
Dr Katharina Wassilew Meeting room "Triaditza" 5 min
15:05 15:15
Workshop Heart

The future of Digital Pathology

All participants are invited and encouraged to expand their network and to explore the possibilities of the platform. The smart in media platform has been used to deliver the slide demonstrations. Mrs Turner is looking forward to demonstrate the system functions for remote histological diagnosis and research, and will be available to discuss its added value in education and will answer all of your questions. This activity is not CPD accredited.

Associate Prof Martin Weihrauch Meeting room "Triaditza" 10 min